Chemotherapy in a Multimodal Treatment Plan

For patients diagnosed with early-stage mesothelioma and who are healthy enough to withstand aggressive cancer treatment, chemotherapy is often combined with other treatments such as surgery and radiation therapy. This is called multimodal therapy, and it offers a chance at long-term survival.

Doctors use the following terms for the timing of when chemotherapy for mesothelioma is delivered.

  • Neoadjuvant chemotherapy is delivered systemically before surgery to shrink tumors and make them easier to remove.
  • Intraoperative chemotherapy is delivered locally during surgery to directly expose cancer cells to chemotherapy.
  • Adjuvant chemotherapy is delivered systemically after surgery to prevent local cancer recurrence.

Intraoperative chemotherapy is only available at top cancer centers, while systemic chemotherapy can be administered at hospitals and other medical facilities.


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